HGMP-RC - UK Human Genome Mapping Project Resource Centre _A_d_d_r_e_s_s: UK HGMP Resource Centre Clinical Research Centre Watford Road Harrow MIDDX HA1 3UJ United Kingdom _E_m_a_i_l: c.bates@CRC.AC.UK _P_h_o_n_e: + 44 81 3466 FAX: + 44 81 869 3807 _D_e_s_c_r_i_p_t_i_o_n In 1990, the UK Medical Research Council (MRC) founded, as part of the UK Human Genome Mapping Project, a Resource Cen- tre (HGMP-RC) at the Clinical Research Centre (CRC), Harrow, Middlesex. The objectives of the HGMP-RC computing are to establish and make available databases of genes, genetic markers and map locations, and to develop new computing environments and methods for acquisition and analysis of such data. Computing and networking facilities were developed by the MRC to provide online computing support to the Project. The facilities are connected to a number of other computing systems in centres of genetics and molecular biology research excellence worldwide through national and interna- tional wide area networks (WAN's) including the European Research Backbone Network (EBONE), INTERNET, Public Data Networks (Packet Switching and Telephone) in the UK and overseas, research and academic networks in the UK and over- seas, European Molecular Biology Network (EMBNet) and oth- ers. Direct connectivity to US laboratories was implemented using a high-speed communication link, the UK-US 'fat pipe'. A great deal of effort has been spent on improving services to the scientific community. Molecular genetics databases, application software and miscellaneous services are _________________________ The information in this section is provided in accor- dance with the copyright notice appearing at the front of this guide. August 29, 1992 NNSC Section 5.48, Page 1 available on the HGMP computer systems and other systems around the world through the HGMP-RC Menu system using workstations, personal computers or terminals from number of manufacturers, equipped with appropriate networking and graphical facilities and connected to any of the above WAN's. _N_e_t_w_o_r_k _A_c_c_e_s_s The HGMP-RC computing facilities can be accessed in two ways: o+ by using the IP (Internet Protocol) service o+ by making an X29 call, using a PAD (packet assembler/disassembler) _W_h_o _C_a_n _U_s_e _t_h_e _U_K _H_G_M_P-_R_C _F_a_c_i_l_i_t_i_e_s Registration is open, subject to the rules of HGMP, to any "bona fide" academic who applies, whether based in the UK or elsewhere. To register as a UK HGMP-RC facilities user please contact the address above (email is not used for registration applications). _R_e_f_e_r_e_n_c_e_s For a detailed description of the system and services avail- able see Rysavy, F.R.,Bishop, M.J. at al., "The UK Human Genome Mapping Project online computing service." "Computer Applications in the Biosciences", Vol.8, no.2. 1992 , Pages 149-154. Several user manuals describing the usage of the HGMP-RC computing facilities have been written and are available to registered users. The user support desk is maintained during working hours, providing practical help with users' problems. A programme of courses aimed at giv- ing an understanding of what the facilities can provide are run regularly. August 29, 1992 NNSC Section 5.48, Page 2